How does VenaSeal™ work?

 

The VenaSeal procedure involves the placement of a very small amount of VenaSeal medical glue into the vein through a small catheter. Once the affected vein is closed, blood is immediately re-routed through other healthy veins in the leg. Unlike other treatments, VenaSeal does not require a regional nerve block or large volumes of anesthesia. Furthermore, there are no pre-procedures drugs involved and patients can return to their normal activities right after the treatment. Unlike heat-based procedures such as endovenous laser or radiofrequency ablation, with VenaSeal there is no risk of skin burns or nerve damage. VenaSeal does not require any immediate post-treatment pain medication or uncomfortable compression stockings.

How effective is the VenaSeal™ procedure?

 

The published success of the VenaSeal closure procedure is up to 98.9% (VeClose study), with far fewer complications than EVLA or surgery.

VenaSeal has been meticulously trialed in the United States and Europe over the last 5 years. Results published show a low risk of complications and excellent medium-term results. The VeClose study out of Germany showed a 98.9% closure rate at 6 months. VenaSeal is considered as effective as endovenous laser ablation but does not involve the use of heat and can, therefore, be performed with the application of a small amount of local anesthetic as opposed to a nerve block or large volumes of tumescent anesthetic.

It is possible to treat two or more veins in the one session. Stockings are usually not necessary and patients are able to return to normal activities immediately. Surface varicose veins are usually treated 2-4 weeks after the VenaSeal procedure with either ultrasound-guided sclerotherapy or ambulatory phlebectomy.

What is VenaSeal™ made of?

 

As you may already know, VenaSeal is a treatment that involves the application of a Medical Grade ‘Superglue’ into the diseased vein, that collapses and permanently seals the vein off. It is a quick, minimally invasive and completely painless procedure that takes approximately 15 minutes in experienced hands.

Venaseal adhesive is a special type of medical super-glue referred to as a ‘Cyanoacrylate’. It is very carefully formulated in specially designed labs and has some unique properties when compared to other medical grade glues on the market.

  • When it comes into contact with blood within the vein wall, it polymerizes rapidly. What this means is that it rapidly seals the vein shut upon application, with minimal migration.
  • It is very soft and elastic so that it is undetectable by the patient after application.
  • Has an “anti-microbial” effect against gram-positive organisms.
  • Has been shown to be extremely safe on administration with no adverse long-term effects.

Where are cyanoacrylates used?

 

Cyanoacrylates have been in use since the 1950s. They have been used in repairing wounds and skin incisions. As an emergency doctor, one of our go-to treatments for children with lacerations was histoacryl blue skin adhesive. It was quick and painless and avoided the need for suturing, particularly when faced with a distressed and alarmed child.

It has also been used in the following areas of medicine:

  • Ophthalmic surgery
  • Cosmetic Procedures
  • Dental
  • Orthopedic

Intravascular Occlusion of Cerebral Arterio-Venous Malformations (AVMs), Varicoceles and Pelvic Congestion Syndrome and Gastric Varices.

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